Karthika Muralidharan is a Kerala-based Indian actress. She is the daughter of C. K. Muraleedharan, a well-known Indian cinematographer. In 2017, she made her acting debut in the Malayalam film Comrade in America, in which she co-starred with Dulquer Salman. Uncle, in which she co-starred with Mammootty, was her second film.
Karthika Muralidharan is best known for her roles in South Indian cinema. Comrade in America, a Malayalam language thriller drama, was one of her 2017 films. The film stars Dulquer Salmaan as Aji Mathew, Chandini Sreedharan, and Priyanka Nair, and is directed by Amal Neerad. She is known for her role in Gireesh Damodar’s 2018 Malayalam thriller drama Uncle.